This section is designed to provide important information regarding reimbursement, the IMBRUVICA® Dose Exchange Program, specialty pharmacies, and other product information.

Such information may be subject to continual change and interpretation. It is provided for informational purposes only and does not guarantee coverage or payment. It is always the provider's responsibility to determine and submit appropriate codes and modifiers based on the services rendered and the provider's medical judgment. Providers should contact the payer for coding and billing guidance.

NDC Numbers for IMBRUVICA® (ibrutinib)

Understanding NDC Numbers

Medications regulated under section 510 of the US Federal Food, Drug, and Cosmetic Act are assigned a unique, 3-segment number known as the National Drug Code (NDC).

NDC numbers for IMBRUVICA®1
10-digit NDC11-digit NDCDescription
57962-420-2857962-0420-28Carton of 28 tablets
420 mg per tablet
57962-280-2857962-0280-28Carton of 28 tablets
280 mg per tablet
57962-014-2857962-0014-28Carton of 28 tablets
140 mg per tablet
57962-140-0957962-0140-09Bottle of 90 capsules
140 mg per capsule
57962-140-1257962-0140-12Bottle of 120 capsules
140 mg per capsule
57962-070-2857962-0070-28Bottle of 28 capsules
70 mg per capsule

Note: The red zero converts the 10-digit NDC to the 11-digit NDC. The red is for emphasis and not for billing purposes.

PLEASE NOTE: Some payers may require that each NDC number be listed on the claim. Payer requirements regarding the use of the 10- or 11-digit NDC may vary. Electronic data exchange generally requires use of the 11-digit NDC, as listed above.


Additional Product Information1

How supplied:

IMBRUVICA® capsules are supplied in white HDPE bottles with a child-resistant closure. Capsules are supplied in 2 dosage strengths:

  • Yellow opaque capsules marked with “ibr 70 mg” in black ink
  • White opaque capsules marked with “ibr 140 mg” in black ink

IMBRUVICA® tablets are available in a carton of one folded blister card containing two 14-count blister strips for a total of 28 tablets. Tablets are supplied in 3 dosage strengths:

  • Yellow-green to green round tablets debossed with “ibr" on one side and "140” on the other side
  • Purple oblong tablets debossed with “ibr” on one side and "280" on the other side
  • Yellow-green to green oblong tablets debossed with “ibr” on one side and "420" on the other side

Storage and handling:

Store IMBRUVICA® in its original packaging at room temperature, 20°C to 25°C (68°F to 77°F). Excursions are permitted between 15°C and 30°C (59°F to 86°F).

HDPE=high-density polyethylene


Reference: 1IMBRUVICA® (ibrutinib) Prescribing Information.